Gastroenterology and Liver

Liver Fibrosis: Assessment and Management

Liver fibrosis is a progressive condition characterized by the accumulation of scar tissue in the liver, often resulting from chronic liver injury. It is a key feature of various liver diseases, including hepatitis C, non-alcoholic fatty liver disease (NAFLD), and alcoholic liver disease. Early detection and accurate assessment of liver fibrosis are essential for managing and potentially reversing the progression of liver disease.

Assessment of liver fibrosis typically involves a combination of clinical evaluation, imaging studies, and liver biopsy. Non-invasive methods, such as elastography and serum biomarkers, have become increasingly important for evaluating fibrosis without the need for invasive procedures. These tools help clinicians monitor disease progression and tailor treatment strategies to individual patients.

Management of liver fibrosis focuses on addressing the underlying cause of liver damage and implementing strategies to halt or reverse fibrosis. Treatment may involve antiviral therapy for viral hepatitis, lifestyle modifications for NAFLD, or abstinence from alcohol. Ongoing research into antifibrotic agents and novel therapeutic approaches aims to improve outcomes for patients with liver fibrosis and prevent progression to cirrhosis.