Gastroenterology and Liver

Peptic Ulcer Disease and H. pylori Infection

Peptic Ulcer Disease (PUD), primarily caused by Helicobacter pylori infection or NSAID use, continues to be a major gastrointestinal issue worldwide. This session provides comprehensive insights into the pathogenesis, clinical presentation, and management of PUD, with a particular focus on the evolving landscape of H. pylori treatment. Although incidence has declined in some regions due to better hygiene and eradication therapy, resistance to standard antibiotics poses a growing challenge. The session explores current diagnostic tools such as urea breath tests, stool antigen testing, and endoscopy, alongside updates on effective eradication regimens including quadruple therapies, tailored treatments, and the role of probiotics. Attendees will also learn about complications such as GI bleeding, perforation, and gastric outlet obstruction. This track emphasizes preventive strategies, including appropriate NSAID use and the role of PPIs, and updates on surveillance for gastric malignancies in high-risk populations. It is essential for clinicians aiming for evidence-based ulcer management.